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The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Gene Name: | carbonyl reductase 4 |
Synonyms: | CBR4, Carbonic reductase 4, Quinone reductase CBR4, Carbonyl reductase 4, SDR45C1 |
Target Sequences: | NM_032783 NP_116172.2 Q8N4T8 |
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