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CASP4 / Caspase 4

caspase 4, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease. The rodent homolog is known as Caspase 4 and Caspase 11.

Gene Name: caspase 4, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP4, CASP-4, Casp11, Caspase 4, Caspase-4, Cysteine protease icerel-ii, ICE(rel)-II, ICE(rel)II, ICH-2, Ich-3, ICH2, Protease ICH-2, TX, Tx protease, Caspase 11, ICEREL-II, Mih1/TX, Protease TX
Target Sequences: NM_001225 NP_001216.1 P49662

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Products
ELISA Kits (22)
Competitive EIA (1)
Custom (3)
Development Kit (1)
Sandwich (15)
Sandwich CLIA (2)
CASP4 / Caspase 4 (22)
Human (8)
Mouse (5)
Rat (1)
Chicken (1)
Guinea pig (1)
Monkey (2)
Porcine (1)
Rabbit (1)
Sheep (1)
Product Group
DevKit DuoPlus (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (1)
96-Well Strip Plate (17)
Antibody Pair and Standard (1)
No (22)
Cell Culture Supernatants (2)
Cell Lysates (2)
Plasma (10)
Serum (10)
Tissue Homogenates (4)
CASP4 / Caspase 4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$798
CASP4 / Caspase 4 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CASP4 / Caspase 4 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
CASP4 / Caspase 4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CASP4 / Caspase 4 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
CASP4 / Caspase 4 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
CASP4 / Caspase 4 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
CASP4 / Caspase 4 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CASP4 / Caspase 4 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
78.125 - 5000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CASP4 / Caspase 4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CASP4 / Caspase 4 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,229; 1000 Wells/$1,826
Viewing 1-22 of 22 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).