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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP14 / Caspase 14

Caspase 14, Apoptosis-related Cysteine Peptidase

CASP14 / Caspase 14 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Gene Name: Caspase 14, Apoptosis-related Cysteine Peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP14, Caspase-14, Caspase 14, MICE, CASP-14
Target Sequences: NM_012114 NP_036246.1 P31944

Filtered by: None
Target
CASP14 / Caspase 14 (85)
Reactivity
Human (55)
Mouse (34)
Rat (23)
Dog (2)
Gerbil (2)
Application
IHC (46)
IHC-Fr (1)
IHC-P (9)
WB (70)
Flo (7)
ELISA (20)
ICC (8)
IF (10)
IP (3)
Peptide-ELISA (1)
Host
rabbit (70)
mouse (14)
goat (1)
Isotype
IgG (14)
IgG1,k (1)
IgG2a,k (7)
Clonality
monoclonal mc (14)
polyclonal pc (71)
Clone
1-71 (1)
70A1426 (2)
Format
AP Conjugated (2)
APC (4)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (9)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (11)
HRP Conjugated (6)
PE Conjugated (7)
Unconjugated (37)
Epitope
aa1-242 (11)
aa1-246 (10)
aa1-257 (10)
aa17-248 (8)
N-Terminus (2)
aa2-18 (2)
110-190 aa, Internal (1)
Internal (1)
aa133-243 (1)
aa163-208 (1)
aa176 (1)
aa223-242 (1)
aa59-93 (1)
Publications
No (84)
Yes (1)
Showing 1-25 of 85 results

CASP14 / Caspase 14 Antibody IHC-plus™ LS-B474
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human CASP14 / Caspase 14
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-Caspase 14 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of caspase-14 in Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with caspase-14 antibody at 1 ug/ml.

CASP14 / Caspase 14 Antibody (N-Terminus) IHC-plus™ LS-B7520
Rabbit Polyclonal to Human CASP14 / Caspase 14
Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $425.00
Anti-Caspase 14 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

CASP14 / Caspase 14 Antibody LS-C148255
Rabbit Polyclonal to Human CASP14 / Caspase 14
Mouse, Dog, Rat, Gerbil, Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00
Western blot of Caspase-14. Tissue lysates (50 ug/lane) and recombinant human Caspase-14 were (Hu C14, 15 ng) were western blotted with Caspase-14 antibody at 1:2000. The antibody detected both the proform of caspase-14, and the large and small subunits of active/cleaved caspase-14.

CASP14 / Caspase 14 Antibody LS-C77969
Rabbit Polyclonal (IgG) to Human CASP14 / Caspase 14
Mouse, Rat, Human
IHC IP WB
Unconjugated
50µl  $465.00

CASP14 / Caspase 14 Antibody LS-C483993
Mouse Monoclonal to Human CASP14 / Caspase 14
Human
ELISA Flo ICC IF
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

CASP14 / Caspase 14 Antibody LS-C483997
Rabbit Polyclonal to Human CASP14 / Caspase 14
Human
ICC IF IHC IHC-P
Unconjugated
50µl  $275.00; 100µl  $355.00

CASP14 / Caspase 14 Antibody (aa1-257) LS-C293199
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00; 10ml 0.5mg/ml  $1,935.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, HRP) LS-C707396
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, Biotin) LS-C684527
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $255.00; 200µl  $305.00; 1ml  $530.00; 10ml  $2,130.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, FITC) LS-C690777
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
FITC Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,325.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, Cy3) LS-C698369
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
Cy3 Conjugated
20µl  $235.00; 100µl  $345.00; 200µl  $415.00; 1ml  $965.00; 10ml  $3,885.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, APC) LS-C715608
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
APC Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $355.00; 1ml  $725.00; 10ml  $4,275.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, PE) LS-C721452
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
PE Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,325.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody (aa1-257, APC, Cy7) LS-C730458
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
APC, Cy7 Conjugated
20µl  $275.00; 100µl  $435.00; 200µl  $575.00; 1ml  $1,455.00; 10ml  $5,820.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody LS-C412551
Rabbit Polyclonal to Human CASP14 / Caspase 14
Human
IF IHC WB
Unconjugated
100µl  $385.00

CASP14 / Caspase 14 Antibody (aa133-243) LS-C306746
Mouse Monoclonal (IgG2a,k) to Human CASP14 / Caspase 14
Human
ELISA IF WB
Unconjugated
100µg  $560.00

CASP14 / Caspase 14 Antibody (Biotin) LS-C521115
Mouse Monoclonal (IgG2a,k) to Human CASP14 / Caspase 14
Human
ELISA IF WB
Biotin Conjugated
100µl  $710.00

CASP14 / Caspase 14 Antibody (FITC) LS-C531159
Mouse Monoclonal (IgG2a,k) to Human CASP14 / Caspase 14
Human
ELISA IF WB
FITC Conjugated
100µl  $710.00

CASP14 / Caspase 14 Antibody (APC) LS-C512898
Mouse Monoclonal (IgG2a,k) to Human CASP14 / Caspase 14
Human
ELISA IF WB
APC Conjugated
100µl  $710.00

CASP14 / Caspase 14 Antibody (PE) LS-C649359
Mouse Monoclonal (IgG2a,k) to Human CASP14 / Caspase 14
Human
ELISA IF WB
PE Conjugated
100µl  $710.00

CASP14 / Caspase 14 Antibody LS-C334785
Rabbit Polyclonal (IgG) to Human CASP14 / Caspase 14
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of HeLa cells.
Western blot analysis of extracts of various cell lines.

CASP14 / Caspase 14 Antibody (aa17-248) LS-C373958
Rabbit Polyclonal to Mouse CASP14 / Caspase 14
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00; 10ml 0.5mg/ml  $1,935.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP14 / Caspase 14 Antibody LS-C109465
Rabbit Polyclonal to Human CASP14 / Caspase 14
Human
ICC IF WB
Unconjugated
100µl  $355.00
Immunofluorescence of paraformaldehyde-fixed HeLa, using Caspase 14 antibody at 1:200 dilution.
Sample (30 ug of whole cell lysate). A: A431. 12% SDS PAGE. CASP14 antibody diluted at 1:1000.

CASP14 / Caspase 14 Antibody (N-Terminus) LS-C153288
Rabbit Polyclonal to Human CASP14 / Caspase 14
Human
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

CASP14 / Caspase 14 Antibody (aa223-242) LS-C313222
Rabbit Polyclonal to Human CASP14 / Caspase 14
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
CASP14 / Caspase 14 antibody. IHC(P): Human Tonsil Tissue.
CASP14 / Caspase 14 antibody. IHC(P): Human Esophagus Squama Cancer Tissue.
Showing 1-25 of 85 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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