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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP12 / Caspase 12

caspase 12

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

Gene Name: caspase 12
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP12, Caspase 12 pseudogene 1, Caspase 12, CASP-12, Caspase 12 (gene/pseudogene), Inactive caspase-12, CASP12P1
Target Sequences: AF486844 CAD13032.1 Q6UXS9

Filtered By: None
Target
CASP12 / Caspase 12 (77)
Reactivity
Human (44)
Mouse (51)
Rat (32)
Application
IHC (55)
IHC-P (9)
WB (69)
Flo (10)
ELISA (26)
ICC (11)
IF (13)
IP (4)
Peptide-ELISA (2)
Host
rabbit (71)
goat (1)
rat (5)
Isotype
IgG (59)
IgG1 (3)
IgG1,k (1)
IgG2a (1)
Clonality
monoclonal mc (5)
polyclonal pc (72)
Clone
12G6 (1)
14F4 (1)
14F7 (1)
G1/G1-4 (1)
Format
AP Conjugated (3)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (9)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (37)
Epitope
aa1-244 (10)
aa1-413 (10)
aa165-193 (8)
aa1-92 (4)
Internal (2)
aa183-205 (2)
aa2-17 (2)
Pro99 (1)
aa100-116 (1)
aa100-117 (1)
aa100-321 (1)
aa158 (1)
aa2-27 (1)
aa232-244 (1)
aa50-99 (1)
aa71-84 (1)
Publications
No (77)
Showing 1-25 of 77 results

CASP12 / Caspase 12 Antibody (aa2-17) IHC-plus™ LS-B747
Rabbit Polyclonal to Mouse CASP12 / Caspase 12
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $495.00
Anti-CASP12 / Caspase 12 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of anti-Caspase-12 (NT) antibody at 1 ug/ml on human (1) and mouse (2) spleen tissue lysate.

CASP12 / Caspase 12 Antibody IHC-plus™ LS-B3785
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Mouse, Rat, Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-CASP12 / Caspase 12 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-CASP12 / Caspase 12 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

CASP12 / Caspase 12 Antibody IHC-plus™ LS-B3645
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Mouse, Rat, Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $425.00
Anti-CASP12 / Caspase 12 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Anti-CASP12 / Caspase 12 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

CASP12 / Caspase 12 Antibody LS-C341
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µg 1mg/ml  $365.00
Immunohistochemical staining of human liver tissue using caspase-12 antibody (small) at 10 ug/mL.
Western blot of caspase-12 in mouse (lane A) and rat (lane B) liver lysate with caspase-12 antibody at 1 ug/ml.

CASP12 / Caspase 12 Antibody (aa165-193) LS-C168327
Rabbit Polyclonal to Human CASP12 / Caspase 12
Human
Flo IF IHC IHC-P WB
Unconjugated
400µl  $305.00
CASP12 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of CASP12 Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

CASP12 / Caspase 12 Antibody (aa165-193) LS-C320009
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo IF IHC WB
Unconjugated
200µl  $530.00

CASP12 / Caspase 12 Antibody (aa165-193, Biotin) LS-C213064
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
Biotin Conjugated
200µl  $680.00

CASP12 / Caspase 12 Antibody (aa165-193, FITC) LS-C213066
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
FITC Conjugated
200µl  $680.00

CASP12 / Caspase 12 Antibody (aa165-193, Azide-free, HRP) LS-C213067
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

CASP12 / Caspase 12 Antibody (aa165-193, PE) LS-C213070
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
PE Conjugated
200µl  $680.00

CASP12 / Caspase 12 Antibody (aa165-193, APC) LS-C213063
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
APC Conjugated
200µl 0.35mg/ml  $680.00

CASP12 / Caspase 12 Antibody (aa165-193, AP) LS-C213065
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA Flo ICC IF IHC WB
AP Conjugated
200µl  $680.00

CASP12 / Caspase 12 Antibody LS-C501103
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Mouse, Human
ELISA IF IHC WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human liver tissue using CASP12 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using CASP12 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CASP12 / Caspase 12 Antibody LS-C661675
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $405.00

CASP12 / Caspase 12 Antibody LS-C393164
Rabbit Polyclonal to Mouse CASP12 / Caspase 12
Mouse, Rat
IF IHC IHC-P WB
Unconjugated
100µl  $305.00

CASP12 / Caspase 12 Antibody (clone G1/G1-4) LS-C189661
Rat Monoclonal [clone G1/G1-4] (IgG2a) to Mouse CASP12 / Caspase 12
Mouse
ELISA IHC IP WB
Unconjugated
25µg 0.5mg/ml  $385.00; 100µg  $475.00

CASP12 / Caspase 12 Antibody (clone 14F7) LS-C179730
Rat Monoclonal [clone 14F7] (IgG1)
Mouse, Rat, Human
ICC IHC IHC-P IP WB
Unconjugated
100µg 1mg/ml  $335.00
Western blot Image

CASP12 / Caspase 12 Antibody (aa183-205) LS-C21336
Rat Monoclonal (IgG1) to Mouse CASP12 / Caspase 12
Mouse
ELISA Flo WB
Unconjugated
100µg  $515.00

CASP12 / Caspase 12 Antibody LS-C405474
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Mouse, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using CASP12 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human lung cancer using CASP12 Polyclonal Antibody at dilution of 1:50.

CASP12 / Caspase 12 Antibody (aa158) LS-C21332
Rabbit Polyclonal (IgG) to Mouse CASP12 / Caspase 12
Mouse
ELISA ICC WB
Unconjugated
100µl  $530.00

CASP12 / Caspase 12 Antibody (aa183-205, clone 12G6) LS-C344951
Rat Monoclonal [clone 12G6] (IgG1,k) to Mouse CASP12 / Caspase 12
Mouse
ELISA Flo WB
Unconjugated
100µg  $365.00
Western blot analysis using anti-caspase-12 (mouse), mAb (12G6) detecting, A) endogenous caspase-12 in mouse lung, liver, spleen and pancreas, and B) pro-caspase-12 in mouse MEF's.

CASP12 / Caspase 12 Antibody (aa1-413) LS-C314590
Rabbit Polyclonal (IgG) to Mouse CASP12 / Caspase 12
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00; 10ml 0.5mg/ml  $1,935.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP12 / Caspase 12 Antibody (aa2-17) LS-C42890
Rabbit Polyclonal (IgG) to Mouse CASP12 / Caspase 12
IHC IHC-P WB
Unconjugated
0.1mg  $415.00

CASP12 / Caspase 12 Antibody (aa71-84) LS-C313224
Rabbit Polyclonal to Human CASP12 / Caspase 12
Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
CASP12 / Caspase 12 antibody. IHC(P): Human Breast Cancer Tissue.
CASP12 / Caspase 12 antibody. IHC(P): Human Lung Cancer Tissue.

CASP12 / Caspase 12 Antibody (Internal) LS-C382447
Rabbit Polyclonal (IgG) to Human CASP12 / Caspase 12
Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Caspase12 antibody
Showing 1-25 of 77 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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