Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
|Gene Name:||calcium/calmodulin-dependent serine protein kinase (MAGUK family)|
|Family/Subfamily:||Protein Kinase , CASK|
|Synonyms:||CASK, CAMGUK, Cask/lin-2, CMG, FGS4, LIN2, MICPCH, HCASK, Protein Kinase Cask, Protein lin-2 homolog, CAGH39, MRXSNA, TNRC8|
|Target Sequences:||NM_003688 NP_003679.2 O14936|
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