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The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.
Gene Name: | Cancer Susceptibility Candidate 4 |
Synonyms: | CASC4, H63, Protein CASC4 |
Target Sequences: | AA411200 |
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