Carboxypeptidase Z / CPZ

carboxypeptidase Z

The major form of CPZ mRNA in human salivary gland encodes a protein with an open reading frame of 641 amino acids. In addition, three variants were found that presumably arise due to alternative intron splicing. The 641 amino acid protein contains an 18 residue signal peptide-like sequence, a 120 residue region that shows 23-29% amino acid identity with a Cys-rich domain found in frizzled proteins and in type XVIII collagen, and then a 390 residue carboxypeptidase domain with 49% amino acid identity to carboxypeptidases E and N. The CPZ activity is more active at neutral pH than at pH 5.5 and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. CPZ is a metallocarboxypeptidase that is active toward substrates with C-terminal basic amino acids.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

Carboxypeptidase Z / CPZ (5)

Publications

No (5)

Tag

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

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Carboxypeptidase Z / CPZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100092

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.5 kDa

Price:

100 µg/$710

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Carboxypeptidase Z / CPZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121584

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.63 kDa

Price:

100 µg/$494

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Human Carboxypeptidase Z / CPZ Protein (Recombinant His-T7) (aa425-652) - LS-G25583

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human Carboxypeptidase Z / CPZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75006

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.5 kDa

Price:

20 µg/$215

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Human Carboxypeptidase Z / CPZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75005

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.63 kDa

Price:

20 µg/$150

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