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Carboxylesterase 1 / CES1

carboxylesterase 1

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

Gene Name: carboxylesterase 1
Synonyms: CES1, ACAT, Brain carboxylesterase hBr1, Carboxylesterase 1, Carboxylesterase 2 (liver), CEH, CES1A1, CES1A2, Cocaine carboxylesterase, Egasyn, HMSE, Liver carboxylesterase 1, HCE-1, PCE-1, Retinyl ester hydrolase, TGH, Triacylglycerol hydrolase, REH, SES1, CE-1, Cholesteryl ester hydrolase, HMSE1, Serine esterase 1
Target Sequences: L07764 AAA16036.1 P23141

Publications (1)

1
The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias. Zabkiewicz J, Gilmour M, Hills R, Vyas P, Bone E, Davidson A, Burnett A, Knapper S. Oncotarget. 2016 7:16650-62. (WB; Human) [Full Text Article] [PubMed:26934551] [PMC:PMC4941341]

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ELISA Kits (4)
Sandwich (4)
Carboxylesterase 1 / CES1 (4)
Human (3)
Rat (1)
96-Well Microplate (1)
96-Well Strip Plate (2)
No (4)
Cell Culture Supernatants (2)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (3)
Serum (4)
Tissue Homogenates (2)
Carboxylesterase 1 / CES1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
Carboxylesterase 1 / CES1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$783
Carboxylesterase 1 / CES1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
28.67 - 7000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
Carboxylesterase 1 / CES1 ELISA Kit
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Sandwich
Human
0.78 - 50 ng/ml
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).