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Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex.
Gene Name: | calpain 8 |
Synonyms: | CAPN8, Calpain 8, Calpain-8, Calpain 8 (nCL-2), NCL-2, NCL2, New calpain 2 |
Target Sequences: | A6NHC0 A6NHC0 |
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