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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CAPN6 / Calpain 6

calpain 6

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Gene Name: calpain 6
Family/Subfamily: Protease , Cysteine C2
Synonyms: CAPN6, CAPNX, Calpain-6, CalpM, Calpain-like protease canpx, Calpain-like protease X-linked, CANPX, DJ914P14.1, Calpain 6, Calpamodulin
Target Sequences: NM_014289 NP_055104.2 Q9Y6Q1

Filtered By: None
Target
CAPN6 / Calpain 6 (26)
Reactivity
Human (25)
Mouse (3)
Rat (4)
Application
IHC (12)
IHC-P (3)
WB (22)
Flo (1)
ELISA (14)
IF (1)
IP (1)
Peptide-ELISA (1)
Host
rabbit (25)
mouse (1)
Isotype
IgG (15)
IgG1 (1)
Clonality
monoclonal mc (1)
polyclonal pc (25)
Clone
1395CT446.22.5 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (10)
Epitope
aa390-419 (8)
C-Terminus (2)
Publications
No (26)
Showing 1-25 of 26 results

CAPN6 / Calpain 6 Antibody (C-Terminus) IHC-plus™ LS-B4597
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-CAPN6 / Calpain 6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of CAPN6 in Human Lung cells with CAPN6 antibody at 20 ug/ml.
Anti-CAPN6 / Calpain 6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of CAPN6 in Human Lung cells with CAPN6 antibody at 20 ug/ml.

CAPN6 / Calpain 6 Antibody LS-C398190
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human lung tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human lung tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at dilution of 1:100.

CAPN6 / Calpain 6 Antibody (HRP) LS-C398192
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

CAPN6 / Calpain 6 Antibody (Biotin) LS-C395455
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

CAPN6 / Calpain 6 Antibody (FITC) LS-C398193
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

CAPN6 / Calpain 6 Antibody LS-C661662
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC IP WB
Unconjugated
100µg  $405.00

CAPN6 / Calpain 6 Antibody (aa390-419) LS-C329311
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

CAPN6 / Calpain 6 Antibody (aa390-419, Biotin) LS-C253378
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

CAPN6 / Calpain 6 Antibody (aa390-419, FITC) LS-C253379
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

CAPN6 / Calpain 6 Antibody (aa390-419, AP) LS-C253376
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

CAPN6 / Calpain 6 Antibody (aa390-419, APC) LS-C253377
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

CAPN6 / Calpain 6 Antibody (aa390-419, Azide-free, HRP) LS-C253380
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

CAPN6 / Calpain 6 Antibody (aa390-419, PE) LS-C253381
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

CAPN6 / Calpain 6 Antibody (clone 1395CT446.22.5) LS-C356266
Mouse Monoclonal [clone 1395CT446.22.5] (IgG1) to Human CAPN6 / Calpain 6
Mouse
Flo Peptide-ELISA WB
Unconjugated
400µl  $305.00
Western blot of lysate from human placenta tissue lysate, using CAPN6 antibody diluted at 1:1000. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20 ug.
Flow cytometric of A549 cells using CAPN6 Antibody (green, Cat#) compared to an isotype control of mouse IgG1(blue). was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.
Western blot of lysate from human placenta tissue lysate, using CAPN6 antibody diluted at 1:1000. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20 ug.
Flow cytometric of A549 cells using CAPN6 Antibody (green, Cat#) compared to an isotype control of mouse IgG1(blue). was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

CAPN6 / Calpain 6 Antibody (aa390-419) LS-C168304
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
CAPN6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CAPN6 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The CAPN6 antibody detected the CAPN6 protein (arrow).
CAPN6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CAPN6 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The CAPN6 antibody detected the CAPN6 protein (arrow).

CAPN6 / Calpain 6 Antibody LS-C400614
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human esophagus cancer using CAPN6 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human esophagus cancer using CAPN6 Polyclonal Antibody at dilution of 1:15.

CAPN6 / Calpain 6 Antibody (C-Terminus) LS-C136923
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Rat, Human
ELISA WB
Unconjugated
100µl  $255.00
Western blot Image
Western blot Image

CAPN6 / Calpain 6 Antibody LS-C748804
Rabbit Polyclonal (IgG) to Human CAPN6 / Calpain 6
Rat, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of rat heart, using CAPN6 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of rat heart, using CAPN6 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.

CAPN6 / Calpain 6 Antibody LS-C663491
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (Biotin) LS-C688497
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (FITC) LS-C695477
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (APC, Cy7) LS-C736280
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $455.00; 200µl  $635.00; 1ml  $1,575.00; 10ml  $6,300.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (APC) LS-C741469
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $375.00; 1ml  $785.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (Cy3) LS-C704283
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.

CAPN6 / Calpain 6 Antibody (PE) LS-C727365
Rabbit Polyclonal to Human CAPN6 / Calpain 6
Human
WB
PE Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western Blot; Sample: Recombinant protein.
Western Blot; Sample: Recombinant protein.
Showing 1-25 of 26 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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