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CAPN5 / Calpain 5

calpain 5

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.

Gene Name: calpain 5
Family/Subfamily: Protease , Cysteine C2
Synonyms: CAPN5, Calpain-5, Calpain htra-3, Calpain-like protease 3, Htra-3, NCL-3, Calpain 5, NCL3, New calpain 3
Target Sequences: NM_004055 NP_004046.2 O15484

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).