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CANX / Calnexin

calnexin

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gene Name: calnexin
Synonyms: CANX, CNX, Calnexin, IP90, p90
Target Sequences: NM_001746 NP_001737.1 P27824

Publications (4)

1
Characterization of zebrafish von Willebrand factor reveals conservation of domain structure, multimerization, and intracellular storage. Ghosh A, Vo A, Twiss BK, Kretz CA, Jozwiak MA, Montgomery RR, Shavit JA. Advances in hematology. 2012 2012:214209. (ICC; Human) [PubMed:23049555] [PMC:PMC3462383]
2
Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins. Wang M, Jokinen J, Tretyakova I, Pushko P, Lukashevich IS. Vaccine. 2018 36:683-690. (WB; Human) [Full Text Article] [PubMed:29287681] Related Antibodies: LS-B6014.
3
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. Luis V Nobre, Katie Nightingale, Benjamin J Ravenhill, Robin Antrobus, Lior Soday, Jenna Nichols, James A Davies, Sepehr Seirafian, Eddie Cy Wang, Andrew J Davison, Gavin Wg Wilkinson, Richard J Stanton, Edward L Huttlin, Michael P Weekes. eLife. 2019 Dec;8:e49894. [Full Text Article] [PubMed:31873071] [PMC:PMC6959991] Related Antibodies: LS-B6881.
4
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy. Marieke C Verweij , Scott G Hansen , Ravi Iyer , Nessy John , Daniel Malouli, David Morrow, Isabel Scholz, Jennie Womack, Shaheed Abdulhaqq, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Julia C Ford, Andrea N Selseth, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Jason Shao, Jonah B Sacha, Michael K Axthelm, Paul T Edlefsen, Jeffrey D Lifson, Louis J Picker, Klaus Früh. Science (New York, N.Y.). 2021 April;372:eabe9233. [Full Text Article] [PubMed:33766941] [PMC:PMC8354429] Related Antibodies: LS-B12410.
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☰ Filters
Products
ELISA Kits (17)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Custom (4)
Sandwich (11)
CANX / Calnexin (17)
Human (6)
Mouse (4)
Rat (5)
Chicken (1)
Dog (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
96-Well Microplate (4)
96-Well Strip Plate (13)
No (17)
Adherent Cell Cultures (2)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (5)
Serum (5)
Tissue Homogenates (3)
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CANX / Calnexin ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
CANX / Calnexin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
CANX / Calnexin ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
CANX / Calnexin ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CANX / Calnexin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CANX / Calnexin ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CANX / Calnexin ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).