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Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
Gene Name: | calcium/calmodulin-dependent protein kinase kinase 1, alpha |
Family/Subfamily: | Protein Kinase , CAMKK |
Synonyms: | CAMKK1, CaM-kinase IV kinase, CaM-kinase kinase 1, CaM-kinase kinase alpha, CAMKK alpha protein, CAMKKA, CaM-KK 1, CaMKK, CaM-KK alpha, CaMKK 1, CaMKK alpha, CAMKKalpha |
Target Sequences: | NM_032294 NP_115670.1 Q8N5S9 |
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