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CAMK2G / CaMK II Gamma
calcium/calmodulin-dependent protein kinase II gamma
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
| Gene Name: | calcium/calmodulin-dependent protein kinase II gamma |
| Family/Subfamily: | Protein Kinase , CAMK2 |
| Synonyms: | CAMK2G, CamKII gamma, CaM kinase II subunit gamma, CaMK, CaMK II gamma, CAMK-II, CAMKG, Gamma CaMK II, CaM kinase II gamma, CaMK-II subunit gamma |
| Target Sequences: | L07044 AAM33514.1 Q13555 |
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