Shipping & Receiving,
2 Shaker Rd Suites
Shirley, MA 01464
Floor 6, Suite 610/620
20700 44th Avenue W
Lynnwood, WA 98036
CAMK2A / CaMKII Alpha belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
|Gene Name:||calcium/calmodulin-dependent protein kinase II alpha|
|Family/Subfamily:||Protein Kinase , CAMK2|
|Synonyms:||CAMK2A, AlphaCaMKII, CaM-kinase II alpha chain, CaMK-II subunit alpha, CAMKA, CaM kinase II alpha, CaMK II alpha, CaMK-II alpha subunit, CaMKIINalpha, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMKII alpha, CaMKIIalpha, KIAA0968|
|Target Sequences:||NM_015981 NP_057065.2 Q9UQM7|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.