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Calcitonin

Calcitonin is formed by the proteolytic cleavage of a larger prepropeptide, which is the product of the CALC1 gene (CALCA). The CALC1 gene belongs to a superfamily of related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin.

Calcitonin Target Details

Target Name: Calcitonin

Publications (4)

1
Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing. Jessika Appelt , Serafeim Tsitsilonis , Ellen Otto , Denise Jahn , Paul Köhli, Anke Baranowsky, Shan Jiang, Melanie Fuchs , Christian H Bucher , Georg N Duda, Karl-Heinz Frosch, Johannes Keller. Cells. 2021 Sep;10:2304. [Full Text Article] [PubMed:34571953] [PMC:PMC8471896]
2
Dietary Calcium and Phosphorus Amounts Affect Development and Tissue-Specific Stem Cell Characteristics in Neonatal Pigs. Wei Zhang, Kellie A Kroscher, Robert L Murray, Rachel Gagliardi, Carly Guiltinan, Robert P Rhoads, Chad H Stahl. The Journal of nutrition. 2020 May;150:1086-1092. [Full Text Article] [PubMed:31965174]
3
Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment. Anke Baranowsky , Denise Jahn , Shan Jiang, Timur Yorgan, Peter Ludewig, Jessika Appelt, Kai K Albrecht, Ellen Otto, Paul Knapstein, Antonia Donat, Jack Winneberger, Lana Rosenthal, Paul Köhli, Cordula Erdmann, Melanie Fuchs, Karl-Heinz Frosch, Serafeim Tsitsilonis, Michael Amling, Thorsten Schinke, Johannes Keller. Bone research. 2022 January;10:9. [Full Text Article] [PubMed:35087025] [PMC:PMC8795393]
4
The calcitonin receptor protects against bone loss and excessive inflammation in collagen antibody-induced arthritis. Tazio Maleitzke, Alexander Hildebrandt, Tamara Dietrich, Jessika Appelt, Denise Jahn, Ellen Otto, Dario Zocholl, Anke Baranowsky, Georg N Duda, Serafeim Tsitsilonis, Johannes Keller. iScience. 2022 January;25:103689. [Full Text Article] [PubMed:35036874] [PMC:PMC8753130]
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Proteins (9)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (1)
Recombinant (7)
Calcitonin (9)
No (9)
6His, N-terminus (3)
6His, N-terminus + Mouse IgG Fc, C-terminus (1)
6His-SUMO, N-terminus (1)
His (1)
His, N-Terminal (1)
His-GST (1)
His-S (1)
Dog (2)
Human (5)
Mouse (1)
Rat (1)
E. coli (6)
HEK 293 Cells (3)
Purified (2)
Calcitonin Protein - Recombinant Calcitonin By SDS-PAGE
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Dog Calcitonin Protein (Recombinant His-S) (Ala26-Arg130) - LS-G24027
E. coli
His-S
15.1 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,601
Calcitonin Protein - Recombinant Calcitonin By SDS-PAGE
Select
Mouse Calcitonin Protein (Recombinant His, N-Terminal) - LS-G24028
E. coli
His, N-Terminal
14.7 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
Select
Rat Calcitonin Protein (Recombinant His) (Cys85-Pro116) - LS-G24029
E. coli
His
16.0kd
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
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Human Calcitonin Protein (Over-Expression Lysate 6His, N-terminus) (Ala26-Asn141) - LS-G26789
HEK 293 Cells
6His, N-terminus
15 kDa
100 µg/$298
Select
Human Calcitonin Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ala26-Asn141) - LS-G26925
HEK 293 Cells
6His, N-terminus
15 kDa
200 µl/$283
Calcitonin Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
Human Calcitonin Protein (Recombinant 6His, N-terminus + Mouse IgG Fc, C-terminus) (Cys85-Pro116) - LS-G26973
HEK 293 Cells
6His, N-terminus + Mouse IgG Fc, C-terminus
35-45 kDa
50 µg/$360; 100 µg/$432; 500 µg/$1,270
Calcitonin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Dog Calcitonin Protein (Recombinant 6His-SUMO, N-terminus) (aa85-116) - LS-G64101
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Calcitonin Protein
Select
Human Calcitonin Protein (Recombinant 6His, N-terminus) (Ala26-Asn141) - LS-G26345
E. coli
6His, N-terminus
15.1 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Calcitonin Protein - Recombinant Calcitonin By SDS-PAGE
Select
Human Calcitonin Protein (Recombinant His-GST) (aa25-85) - LS-G12209
E. coli
His-GST
38.6 kDa
10 µg/$261; 50 µg/$338; 100 µg/$510; 200 µg/$637; 1 mg/$1,616; 500 µg/$1,207; 5 mg/$2,554; 2 mg/$1,788
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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