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Calcitonin

Calcitonin is formed by the proteolytic cleavage of a larger prepropeptide, which is the product of the CALC1 gene (CALCA). The CALC1 gene belongs to a superfamily of related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin.

Calcitonin Target Details

Target Name: Calcitonin

Publications (4)

1
Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing. Jessika Appelt , Serafeim Tsitsilonis , Ellen Otto , Denise Jahn , Paul Köhli, Anke Baranowsky, Shan Jiang, Melanie Fuchs , Christian H Bucher , Georg N Duda, Karl-Heinz Frosch, Johannes Keller. Cells. 2021 Sep;10:2304. [Full Text Article] [PubMed:34571953] [PMC:PMC8471896]
2
Dietary Calcium and Phosphorus Amounts Affect Development and Tissue-Specific Stem Cell Characteristics in Neonatal Pigs. Wei Zhang, Kellie A Kroscher, Robert L Murray, Rachel Gagliardi, Carly Guiltinan, Robert P Rhoads, Chad H Stahl. The Journal of nutrition. 2020 May;150:1086-1092. [Full Text Article] [PubMed:31965174]
3
Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment. Anke Baranowsky , Denise Jahn , Shan Jiang, Timur Yorgan, Peter Ludewig, Jessika Appelt, Kai K Albrecht, Ellen Otto, Paul Knapstein, Antonia Donat, Jack Winneberger, Lana Rosenthal, Paul Köhli, Cordula Erdmann, Melanie Fuchs, Karl-Heinz Frosch, Serafeim Tsitsilonis, Michael Amling, Thorsten Schinke, Johannes Keller. Bone research. 2022 January;10:9. [Full Text Article] [PubMed:35087025] [PMC:PMC8795393]
4
The calcitonin receptor protects against bone loss and excessive inflammation in collagen antibody-induced arthritis. Tazio Maleitzke, Alexander Hildebrandt, Tamara Dietrich, Jessika Appelt, Denise Jahn, Ellen Otto, Dario Zocholl, Anke Baranowsky, Georg N Duda, Serafeim Tsitsilonis, Johannes Keller. iScience. 2022 January;25:103689. [Full Text Article] [PubMed:35036874] [PMC:PMC8753130]
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).