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CALCA encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
|Gene Name:||Calcitonin-Related Polypeptide Alpha|
|Family/Subfamily:||Hormone , not assigned-Hormone|
|Synonyms:||CALCA, Alpha-type CGRP, CGRP, CGRP-I, CGRP1, CT, Calcitonin, KC, CALC1, Calcitonin 1, Katacalcin|
|Target Sequences:||NM_001741 NP_001732.1 P01258|
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