CALB2 / Calretinin

calbindin 2

Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin 2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31520 Da, and shares 58% identical residues with human calbindin 1. Calbindin 2 contains five presumably active and one presumably inactive calcium-binding domains. Comparison with the partial sequences available for chick and guinea pig calbindin 2 reveals that the protein is highly conserved in evolution. The calbindin 2 message was detected in the brain, while absent from heart muscle, kidney, liver, lung, spleen, stomach and thyroid gland. There are two additional forms of alternatively spliced calbindin 2 mRNAs encoding C-terminally truncated proteins. Exon 7 can splice to exon 9, resulting in a frame shift and a translational stop at the second codon of exon 9, and encoding calretinin-20k. Exon 7 can also splice to exon 10, resulting in a frame shift and a translational stop at codon 15 of exon 10, and encoding calretinin-22k. The truncated proteins are able to bind calcium.

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Products

ELISA Kits (21)

Type

Custom (5)

Sandwich (14)

Sandwich CLIA (2)

Target

CALB2 / Calretinin (21)

Reactivity

Human (6)

Mouse (3)

Rat (5)

Chicken (2)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (17)

Publications

No (21)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (11)

Serum (11)

Tissue Homogenates (4)

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Human CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F21971

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F4544

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Chicken CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F41888

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

7.813 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F41889

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F41890

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F41891

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F41892

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

7.813 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human CALB2 / Calretinin (Custom ELISA) ELISA Kit - LS-F15032

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken CALB2 / Calretinin (Custom ELISA) ELISA Kit - LS-F15034

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Mouse CALB2 / Calretinin (Custom ELISA) ELISA Kit - LS-F15033

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine CALB2 / Calretinin (Custom ELISA) ELISA Kit - LS-F15030

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat CALB2 / Calretinin (Custom ELISA) ELISA Kit - LS-F15031

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat CALB2 / Calretinin (CLIA) ELISA Kit - LS-F31140

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human CALB2 / Calretinin (CLIA) ELISA Kit - LS-F29503

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Mouse CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F40291

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Rat CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F22798

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Rat CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F27390

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

25 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F26767

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

50 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Mouse CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F36229

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F36801

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CALB2 / Calretinin (Sandwich ELISA) ELISA Kit - LS-F35442

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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