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C4BPB / C4BP Beta

complement component 4 binding protein, beta

C4BPB / C4BP Beta is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

Gene Name: complement component 4 binding protein, beta
Synonyms: C4BPB, C4b-binding protein beta chain, C4BP
Target Sequences: NM_000716 NP_000707.1 P20851

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Products
Proteins (15)
Over-Expression Lysate (8)
Recombinant (7)
C4BPB / C4BP Beta (15)
No (15)
GST (1)
His (2)
Myc-DDK (Flag) (12)
Human (11)
293T Cells (4)
E. coli (2)
HEK 293 Cells (8)
Wheat Germ Extract (1)
Purified (2)
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.29 kDa
100 µg/$494
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.29 kDa
100 µg/$494
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.29 kDa
100 µg/$494
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.29 kDa
100 µg/$494
C4BPB / C4BP Beta Protein - 12.5% SDS-PAGE of human C4BPB stained with Coomassie Blue
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Wheat Germ Extract
GST
53.35 kDa
10 µg/$479; 25 µg/$670
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.29 kDa
20 µg/$150
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.29 kDa
20 µg/$150
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.29 kDa
20 µg/$150
C4BPB / C4BP Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.29 kDa
20 µg/$150
C4BPB / C4BP Beta Protein - Purified recombinant protein C4BPB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.2 kDa
20 µg/$1,107
C4BPB / C4BP Beta Protein - Purified recombinant protein C4BPB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.3 kDa
20 µg/$1,107
C4BPB / C4BP Beta Protein - Purified recombinant protein C4BPB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
26.2 kDa
20 µg/$1,107
C4BPB / C4BP Beta Protein - Purified recombinant protein C4BPB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
26.3 kDa
20 µg/$1,107
C4BPB / C4BP Beta Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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E. coli
His
27.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).