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C4.4A / LYPD3

LY6/PLAUR domain containing 3

C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter. C4.4A expression has also been found to be upregulated in breast tumors when compare to normal breast tissue.

Gene Name:	LY6/PLAUR domain containing 3
Synonyms:	LYPD3, C4.4A, MIG-C4, LY6/PLAUR domain containing 3
Target Sequences:	NM_014400 NP_055215.2 O95274

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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