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Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
Gene Name: | Chromosome 17 Open Reading Frame 70 |
Synonyms: | C17orf70, FAAP100 |
Target Sequences: | NM_025161 NP_079437.5 Q0VG06 |
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