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Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
Gene Name: | chromosome 11 open reading frame 73 |
Synonyms: | C11orf73, Hikeshi, HSPC138, HSPC179, L7RN6, Protein Hikeshi, Lethal, Chr 7, Rinchik 6 |
Target Sequences: | NM_016401 NP_057485.2 Q53FT3 |
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