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C-TAK1 / MARK3

MAP/microtubule affinity-regulating kinase 3

MARK3, a MARK type protein kinase, was originally identified as a marker induced with DNA damaging agents. The protein contains a N-terminal kinase domain. It has been shown to bind and phosphorylate CDC25C and to regulate Ras signaling by phosphorylating the MAPK scaffold, KSR1. At least three mRNA transcripts have been reported -- 3.0-, 3.1-, and 3.8-kb. Loss of MARK3 has been associated with carcinogenesis in the pancreas.

Gene Name: MAP/microtubule affinity-regulating kinase 3
Family/Subfamily: Protein Kinase , MARK
Synonyms: MARK3, C-TAK1, ELKL motif kinase 2, EMK2, Etk-1, KP78, PAR1A, Ser/Thr protein kinase PAR-1, Par-1a, CTAK1, EMK-2, Protein kinase STK10
Target Sequences: NM_002376 NP_002367.5 P27448

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
C-TAK1 / MARK3 (10)
No (10)
GST (1)
GST, N-terminus (2)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (5)
Human (8)
293T Cells (2)
Baculovirus (1)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (3)
Purified (2)
Low endotoxin level (1)
C-TAK1 / MARK3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
74 kDa
100 µg/$494
C-TAK1 / MARK3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
C-TAK1 / MARK3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
His, N-Terminal
74 kDa
50 µg/$419
C-TAK1 / MARK3 Protein - 12.5% SDS-PAGE of human MARK3 stained with Coomassie Blue
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Wheat Germ Extract
GST
107.8 kDa
10 µg/$479; 25 µg/$670
C-TAK1 / MARK3 Protein - Purified recombinant protein MARK3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
81.3 kDa
20 µg/$1,107
C-TAK1 / MARK3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
74 kDa
20 µg/$150
C-TAK1 / MARK3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
81.3 kDa
20 µg/$150
C-TAK1 / MARK3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
81.3 kDa
100 µg/$494
Select
Baculovirus
His-GST
Less than 1.0 EU/µg protein (determined by LAL method).
109.3 kDa
50 µg/$707
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).