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BTN3A3
Butyrophilin, Subfamily 3, Member A3
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).
| Gene Name: | Butyrophilin, Subfamily 3, Member A3 |
| Synonyms: | BTN3A3, Butyrophilin 3 |
| Target Sequences: | NM_006994 NP_008925.1 O00478 |
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