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BTN3A1 / CD277

butyrophilin, subfamily 3, member A1

Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Gene Name: butyrophilin, subfamily 3, member A1
Synonyms: BTN3A1, BT3.1, CD277 antigen, BTF5, CD277
Target Sequences: NM_007048 NP_008979.3 O00481

Publications (2)

1
Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on V?9Vd2 T cell activation. Gu S, Sachleben JR, Boughter CT, Nawrocka WI, Borowska MT, Tarrasch JT, Skiniotis G, Roux B, Adams EJ. Proceedings of the National Academy of Sciences of the United States of America. 2017 August;114:E7311-E7320. (Human) [Full Text Article] [PubMed:28807997] [PMC:PMC5584448] Related Antibodies: LS-C319905.
2
Regulation of Human ?d T Cells by BTN3A1 Protein Stability and ATP-Binding Cassette Transporters. Rhodes DA, Chen HC, Williamson JC, Hill A, Yuan J, Smith S, Rhodes H, Trowsdale J, Lehner PJ, Herrmann T, Eberl M. Frontiers in immunology. 2018 April;9:662. [Full Text Article] [PubMed:29670629] [PMC:PMC5893821]

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
BTN3A1 / CD277 (10)
No (10)
6His, N-terminus (1)
Fc, C-terminus (1)
Fc-AVI, C-terminus (1)
His-SUMO (1)
Myc-DDK (Flag) (5)
Human (8)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Human (2)
Mammalian Cells (1)
Yeast (1)
Purified (1)
Low endotoxin level (3)
BTN3A1 / CD277 Protein - Purified recombinant protein BTN3A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
57.5 kDa
20 µg/$1,107
Select
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
50.8kD
10 µg/$266; 50 µg/$343; 500 µg/$1,377
BTN3A1 / CD277 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
BTN3A1 / CD277 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
57.5 kDa
100 µg/$710
BTN3A1 / CD277 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.6 kDa
100 µg/$494
Select
E. coli
His-SUMO
40.14 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
BTN3A1 / CD277 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.6 kDa
20 µg/$150
BTN3A1 / CD277 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
57.5 kDa
20 µg/$215
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
50.8 kDa
10 µg/$266; 50 µg/$339
BTN3A1 / CD277 Protein - Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated
Select
Human
Fc-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.6 kDa
20 µg/$416; 100 µg/$910
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).