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RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Gene Name: | CUGBP, Elav-like family member 6 |
Synonyms: | CELF6, BRUNOL6, Bruno-like protein 6, CELF-6, CUG-BP and ETR-3 like factor 6, RNA-binding protein BRUNOL-6 |
Target Sequences: | Q96J87 Q96J87 |
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