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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BRUCE / BIRC6

baculoviral IAP repeat containing 6

Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

Gene Name: baculoviral IAP repeat containing 6
Synonyms: BIRC6, APOLLON, BRUCE, KIAA1289
Target Sequences: NM_016252 NP_057336.3 Q9NR09

Filtered by: None
Target
BRUCE / BIRC6 (25)
Reactivity
Human (24)
Mouse (5)
Rat (1)
Bat (1)
Chicken (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (2)
Pig (1)
Rabbit (1)
Xenopus (1)
Zebrafish (1)
Application
IHC (13)
IHC-P (2)
WB (11)
Flo (1)
ELISA (13)
IP (1)
Peptide-ELISA (2)
Host
rabbit (23)
goat (2)
Isotype
Ig (1)
IgG (14)
Clonality
polyclonal pc (25)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (12)
Epitope
aa4576-4857 (8)
N-Terminus (7)
aa4775-C-term (2)
C-Terminus (1)
aa4724-4735 (1)
aa4845-4857 (1)
Publications
No (25)
Showing 1-25 of 25 results

IHC-plus™ BRUCE / BIRC6 Antibody LS-B4702
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC, IHC-P
Unconjugated
50µg 1mg/ml  $545.00
Anti-BIRC6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ BRUCE / BIRC6 Antibody (aa4845-4857) LS-B8292
Goat Polyclonal to Human BRUCE / BIRC6
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-BRUCE / BIRC6 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.

BRUCE / BIRC6 Antibody (C-Terminus) LS-C757988
Rabbit Polyclonal (Ig) to Human BRUCE / BIRC6
Human
ELISA, Flo, WB
Unconjugated
200µl  $325.00
All lanes: Anti-BIRC6 Antibody (C-Term) at 1:1000 dilution Lane 1: SH-SY5Y whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 530 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Overlay histogram showing Hela cells stained with BIRC6 Antibody (C-Term) (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (BIRC6 Antibody (C-Term), 1:25 dilution) for 60 min at 37°C. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed (OE188374) at 1/200 dilution for 40 min at 37°C. Isotype control antibody (blue line) was rabbit IgG1 (1µg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed.

BRUCE / BIRC6 Antibody (aa4775-C-term) LS-C287263
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Mouse, Human
IHC, IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human BIRC6/Apollon by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:5000 (0.2 ug/ml).

BRUCE / BIRC6 Antibody LS-C402806
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Mouse, Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human ovarian cancer using BIRC6 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human ovarian cancer using BIRC6 Polyclonal Antibody at dilution of 1:30.

BRUCE / BIRC6 Antibody LS-C405451
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Mouse, Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human liver cancer using BIRC6 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human liver cancer using BIRC6 Polyclonal Antibody at dilution of 1:50.

BRUCE / BIRC6 Antibody LS-C406047
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Mouse, Human
ELISA, IHC
Unconjugated
20µl 0.1mg/ml  $205.00; 60µl 0.1mg/ml  $235.00; 120µl 0.1mg/ml  $295.00; 200µl 0.1mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human gastric cancer using BIRC6 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human gastric cancer using BIRC6 Polyclonal Antibody at dilution of 1:40.

BRUCE / BIRC6 Antibody LS-C803719
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

BRUCE / BIRC6 Antibody (N-Terminus) LS-C77057
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
ELISA
Unconjugated
200µl  $530.00

BRUCE / BIRC6 Antibody (N-Terminus, Biotin) LS-C206409
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
Biotin Conjugated
200µl  $680.00

BRUCE / BIRC6 Antibody (N-Terminus, FITC) LS-C206410
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
FITC Conjugated
200µl  $680.00

BRUCE / BIRC6 Antibody (N-Terminus, AP) LS-C206407
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
AP Conjugated
200µl  $680.00

BRUCE / BIRC6 Antibody (N-Terminus, APC) LS-C206408
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
APC Conjugated
200µl  $680.00

BRUCE / BIRC6 Antibody (N-Terminus, PE) LS-C206411
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
PE Conjugated
200µl  $680.00

BRUCE / BIRC6 Antibody (N-Terminus, Azide-free, HRP) LS-C207938
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
ELISA, IHC
HRP Conjugated, Azide-free
200µl  $680.00

BRUCE / BIRC6 Antibody (aa4775-C-term) LS-C286393
Rabbit Polyclonal (IgG) to Human BRUCE / BIRC6
Human
IHC
Unconjugated
100µl  $415.00
Detection of Human BIRC6/Apollon by Immunohistochemistry. Sample: FFPE section of human ovarian tumor. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:250.
Detection of Human BIRC6/Apollon by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:250.

BRUCE / BIRC6 Antibody (aa4576-4857) LS-C373245
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, HRP) LS-C712967
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
HRP Conjugated
100µl 0.5mg/ml  $285.00; 200µl 0.5mg/ml  $345.00; 1ml 0.5mg/ml  $680.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, Biotin) LS-C688267
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
Biotin Conjugated
100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, FITC) LS-C695198
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
FITC Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $325.00; 1ml 0.5mg/ml  $635.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, PE) LS-C727028
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
PE Conjugated
100µl 0.1mg/ml  $245.00; 200µl 0.1mg/ml  $285.00; 1ml 0.1mg/ml  $475.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, Cy3) LS-C703944
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
Cy3 Conjugated
100µl 0.1mg/ml  $355.00; 200µl 0.1mg/ml  $445.00; 1ml 0.1mg/ml  $1,050.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, APC, Cy7) LS-C735951
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
APC, Cy7 Conjugated
100µl 0.1mg/ml  $385.00; 200µl 0.1mg/ml  $475.00; 1ml 0.1mg/ml  $1,170.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4576-4857, APC) LS-C741295
Rabbit Polyclonal to Human BRUCE / BIRC6
Human
WB
APC Conjugated
100µl 0.1mg/ml  $275.00; 200µl 0.1mg/ml  $315.00; 1ml 0.1mg/ml  $590.00
Western blot of BRUCE / BIRC6 antibody.

BRUCE / BIRC6 Antibody (aa4724-4735) LS-C139652
Goat Polyclonal to Human BRUCE / BIRC6
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100µg 0.5mg/ml  $335.00
Showing 1-25 of 25 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).