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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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BRAK / CXCL14
chemokine (C-X-C motif) ligand 14
This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
| Gene Name: | chemokine (C-X-C motif) ligand 14 |
| Family/Subfamily: | Intercrine , Intercrine alpha |
| Synonyms: | CXCL14, BRAK, C-X-C motif chemokine 14, Bolekine, Breast and kidney, Chemokine BRAK, KS1, Mip2 gamma, MIP2G, SCYB14, Small-inducible cytokine B14, MIP-2 gamma, BMAC, Tumor-suppressing chemokine, KEC, MIP-2g, NJAC |
| Target Sequences: | NM_004887 NP_004878.2 O95715 |
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