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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BRAF / B-Raf

v-raf murine sarcoma viral oncogene homolog B

BRAF / B-Raf is a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Gene Name: v-raf murine sarcoma viral oncogene homolog B
Family/Subfamily: Protein Kinase , Raf
Synonyms: BRAF, 94 kDa B-raf protein, B-raf, BRAF1, B Raf, Proto-oncogene B-Raf, p94, B-RAF1, NS7, ONCOGENE BRAF, RAFB1
Target Sequences: NM_004333 NP_004324.2 P15056

Filtered by: None
Over-Expression Lysate (2)
Recombinant (4)
BRAF / B-Raf (6)
GST,N-terminus (1)
His (1)
His, N-Terminal (1)
Myc + DDK (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
Biologically Active
Biologically active (1)
No (6)
Showing 1-6 of 6 results

Human BRAF / B-Raf Protein (Recombinant GST,N-terminus) (aa346-445) - LS-G57923
Wheat Germ Extract
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Human BRAF / B-Raf Protein (Recombinant His, N-Terminal) (aa432-766) - LS-G134464
E. coli
His, N-Terminal
5µg  $195.00; 20µg  $255.00; 1mg  $3,780.00

Human BRAF / B-Raf Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G74692
293T Cells
Myc + DDK
84.3 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BRAF / B-Raf Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G100267
HEK 293 Cells
Myc + DDK
84.3 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human BRAF / B-Raf Protein (Recombinant His) - LS-G3200
E. coli
100µg 0.25mg/ml  $365.00; 0.5mg 0.25mg/ml  $935.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human BRAF / B-Raf Protein (Recombinant Myc + DDK) (Full Length) - LS-G65036
HEK 293 Cells
Myc + DDK
Biologically active
84.3 kDa
20µg  $890.00
Purified recombinant protein BRAF was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Showing 1-6 of 6 results


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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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