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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BP1 / DLX4

distal-less homeobox 4

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.

Gene Name: distal-less homeobox 4
Synonyms: DLX4, Beta protein 1, BP1, DLX7, DLX8, DLX9, Distal-less homeo box 7, Distal-less homeo box 9, Distal-less homeobox 4, Homeobox protein DLX-7, Homeobox protein DLX-8, Homeobox protein DLX-4
Target Sequences: NM_001934 NP_001925.2 Q92988

Publications (2)

1
BP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells. Stevenson HS, Fu SW, Pinzone JJ, Rheey J, Simmens SJ, Berg PE. Breast cancer research : BCR. 2007 9:R60. (WB; Human) [PubMed:17854498] [PMC:PMC2242656]
2
Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis. Yin J, Wei ZJ, Li KB, Cao YZ, Guo W. International journal of biological sciences. 2010 6:491-8. [PubMed:20827401] [PMC:PMC2935671]

Filtered By: None
Target
BP1 / DLX4 (69)
Reactivity
Human (57)
Mouse (25)
Rat (16)
Bat (4)
Bovine (12)
Chimpanzee (15)
Dog (8)
Gibbon (6)
Monkey (12)
Orangutan (6)
Pig (8)
Rabbit (8)
Application
IHC (10)
IHC-P (6)
WB (64)
Flo (4)
DB (2)
ELISA (12)
ICC (3)
IF (4)
IP (7)
Peptide-ELISA (1)
RNAi (1)
Host
rabbit (61)
mouse (4)
rat (4)
Isotype
IgG (36)
IgG1 (4)
IgG2a (3)
IgG2a,k (1)
Clonality
monoclonal mc (8)
polyclonal pc (61)
Clone
1F11 (1)
350C3a (2)
FG35.4 (4)
Format
AP Conjugated (2)
APC Conjugated (2)
Biotin Conjugated (12)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (11)
HRP Conjugated (10)
PE Conjugated (3)
Unconjugated (26)
Epitope
aa72-100 (8)
aa1-60 (6)
C-Terminus (4)
N-Terminus (4)
aa151-200 (4)
aa31-80 (4)
aa38-87 (4)
aa57-106 (4)
aa72-121 (4)
aa74-123 (4)
30-110 aa, Internal (1)
Gln90 (1)
aa61-110 (1)
Publications
No (69)
Showing 1-25 of 69 results

BP1 / DLX4 Antibody (aa1-60) IHC-plus™ LS-B666
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $425.00
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody (aa1-60, Biotin) LS-C141173
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC IHC-P IP WB
Biotin Conjugated
100µl  $365.00
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody (aa1-60, DY488) LS-C141154
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC IHC-P IP WB
DY488 Conjugated
100µl  $365.00
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody (aa1-60, DY550) LS-C141156
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC IHC-P IP WB
DY550 Conjugated
100µl  $365.00
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody (aa1-60, DY650) LS-C141174
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC IHC-P IP WB
DY650 Conjugated
100µl  $365.00
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DLX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lanes: 1. BP1-specific band (36kDa) from 10ug of cell extract using anti-BP1 (BP1  Antibody)antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (BP1  Antibody) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody LS-C64737
Mouse Monoclonal (IgG2a) to Human BP1 / DLX4
Human
ICC WB
Unconjugated
50µg 0.05mg/ml  $385.00

BP1 / DLX4 Antibody (aa57-106) LS-C30645
Rabbit Polyclonal (IgG) to Mouse BP1 / DLX4
Mouse, Rat
WB
Unconjugated
100µg  $325.00
NIH 3T3 Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
NIH 3T3 Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BP1 / DLX4 Antibody LS-C753209
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

BP1 / DLX4 Antibody (30-110 aa, Internal) LS-C383154
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Dlx-4 antibody
Western blot of Dlx-4 antibody

BP1 / DLX4 Antibody (clone 350C3a) LS-C342675
Mouse Monoclonal [clone 350C3a] (IgG2a) to Human BP1 / DLX4
Human
DB ICC IF WB
Unconjugated
100µg 0.1mg/ml  $375.00
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-DLX4 mAb.
Western blot analysis of immunized recombinant protein, using anti-DLX4 monoclonal antibody.
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-DLX4 mAb.
Western blot analysis of immunized recombinant protein, using anti-DLX4 monoclonal antibody.

BP1 / DLX4 Antibody (Gln90) LS-C177028
Rabbit Polyclonal to Human BP1 / DLX4
Human
IF IHC IHC-P WB
Unconjugated
100µl  $345.00
IHC of Dlx-4 (Q90) pAb in paraffin-embedded human liver carcinoma tissue.
Western blot of Dlx-4 (Q90) pAb in extracts from COLO cells.
IHC of Dlx-4 (Q90) pAb in paraffin-embedded human liver carcinoma tissue.
Western blot of Dlx-4 (Q90) pAb in extracts from COLO cells.

BP1 / DLX4 Antibody (clone 1F11) LS-C197058
Mouse Monoclonal [clone 1F11] (IgG2a,k) to Human BP1 / DLX4
Human
ELISA IP RNAi WB
Unconjugated
100µg  $355.00
Western Blot analysis of DLX4 expression in transfected 293T cell line by DLX4 monoclonal antibody (M01), clone 1F11.Lane 1: DLX4 transfected lysate(26 KDa).Lane 2: Non-transfected lysate.
Immunoprecipitation of DLX4 transfected lysate using anti-DLX4 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with DLX4 rabbit polyclonal antibody.
Western Blot analysis of DLX4 expression in transfected 293T cell line by DLX4 monoclonal antibody (M01), clone 1F11.Lane 1: DLX4 transfected lysate(26 KDa).Lane 2: Non-transfected lysate.
Immunoprecipitation of DLX4 transfected lysate using anti-DLX4 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with DLX4 rabbit polyclonal antibody.

BP1 / DLX4 Antibody (clone 350C3a) LS-C184642
Mouse Monoclonal [clone 350C3a] (IgG2a) to Human BP1 / DLX4
Human
DB ICC WB
Unconjugated
50µg 0.1mg/ml  $325.00
Western blot of immunized recombinant protein using DLX4 antibody.
Western blot of immunized recombinant protein using DLX4 antibody.

BP1 / DLX4 Antibody (aa1-60) LS-C64736
Rabbit Polyclonal to Human BP1 / DLX4
Human
IHC WB
Unconjugated
100µl  $515.00

BP1 / DLX4 Antibody LS-C401607
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using DLX4 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using DLX4 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using DLX4 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using DLX4 Polyclonal Antibody at dilution of 1:50.

BP1 / DLX4 Antibody (aa72-100) LS-C320860
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
Unconjugated
200µl  $530.00

BP1 / DLX4 Antibody (aa72-100, Biotin) LS-C520222
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

BP1 / DLX4 Antibody (aa72-100, FITC) LS-C213593
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
FITC Conjugated
200µl  $680.00

BP1 / DLX4 Antibody (aa72-100, AP) LS-C213591
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
AP Conjugated
200µl  $680.00

BP1 / DLX4 Antibody (aa72-100, APC) LS-C213592
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
APC Conjugated
200µl  $680.00

BP1 / DLX4 Antibody (aa72-100, PE) LS-C213595
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
ELISA WB
PE Conjugated
200µl  $680.00

BP1 / DLX4 Antibody LS-C404902
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Mouse, Human
ELISA WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Western blot analysis of Mouse brain tissue, using DLX4 Polyclonal Antibody at dilution of 1:900.
Western blot analysis of Mouse brain tissue, using DLX4 Polyclonal Antibody at dilution of 1:900.

BP1 / DLX4 Antibody (clone FG35.4) LS-C350354
Rat Monoclonal [clone FG35.4] (IgG1) to Mouse BP1 / DLX4
Mouse
Flo
Unconjugated
500µg 0.5mg/ml  $355.00

BP1 / DLX4 Antibody LS-C310148
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
IP WB
Unconjugated
100µl  $605.00

BP1 / DLX4 Antibody (aa61-110) LS-C119193
Rabbit Polyclonal (IgG) to Human BP1 / DLX4
Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from COLO cells, using DLX4 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from COLO cells, using DLX4 Antibody. The lane on the right is blocked with the synthesized peptide.
Showing 1-25 of 69 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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