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BMP10

bone morphogenetic protein 10

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Gene Name: bone morphogenetic protein 10
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP10, BMP-10, Bone morphogenetic protein 10
Target Sequences: NM_014482 NP_055297.1 O95393

Publications (1)

1
Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. Nicola E Owen, Graeme J Alexander, Sambit Sen, Katherine Bunclark, Gary Polwarth, Joanna Pepke-Zaba, Anthony P Davenport, Nicholas W Morrell, Paul D Upton. EBioMedicine. 2020 Jun;56:102794. [Full Text Article] [PubMed:32454407] [PMC:PMC7248419] Related Antibodies: LS-C293026.

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Products
ELISA Kits (18)
Custom (2)
Sandwich (14)
Sandwich CLIA (2)
BMP10 (18)
Human (7)
Mouse (4)
Rat (3)
Chicken (1)
Monkey (1)
Pig (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (12)
No (18)
Cell Culture Supernatants (3)
Citrate Plasma (3)
EDTA Plasma (3)
Heparin Plasma (3)
Plasma (10)
Serum (13)
Tissue Homogenates (3)
BMP10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
BMP10 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$863
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
BMP10 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
BMP10 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
BMP10 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
BMP10 ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
BMP10 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
13.72 - 10000 pg/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$990
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
BMP10 ELISA Kit
Select
Sandwich
Human
15.6 - 1000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
BMP10 ELISA Kit
Select
Sandwich
Mouse
15.6 - 1000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).