BLNK

B-cell linker

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.

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Products

ELISA Kits (13)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (4)

Sandwich (6)

Target

BLNK (13)

Reactivity

Human (5)

Mouse (4)

Rat (2)

Chicken (2)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (10)

Publications

No (13)

Sample Type

Adherent Cell Cultures (3)

Plasma (1)

Serum (1)

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Mouse BLNK (Custom ELISA) ELISA Kit - LS-F18087

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken BLNK (Custom ELISA) ELISA Kit - LS-F18089

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human BLNK (Custom ELISA) ELISA Kit - LS-F18088

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat BLNK (Custom ELISA) ELISA Kit - LS-F18090

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Monkey BLNK (Sandwich ELISA) ELISA Kit - LS-F41602

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit BLNK (Sandwich ELISA) ELISA Kit - LS-F41604

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Chicken BLNK (Sandwich ELISA) ELISA Kit - LS-F41600

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Guinea pig BLNK (Sandwich ELISA) ELISA Kit - LS-F41601

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Porcine BLNK (Sandwich ELISA) ELISA Kit - LS-F41603

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Human BLNK (Sandwich ELISA) ELISA Kit - LS-F37833

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse/Human/Rat Phospho-BLNK (Tyr84) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1707

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human BLNK (Cell-Based ELISA) ELISA Kit - LS-F1830

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

Select

Mouse/Human Phospho-BLNK (Tyr96) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1244

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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