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BID

BH3 interacting domain death agonist

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myristoylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.

Gene Name: BH3 interacting domain death agonist
Family/Subfamily: Apoptosis
Synonyms: BID, Apoptic death agonist, BID isoform L(2), BID isoform Si6, Bh3, FP497, p22 BID, BID isoform ES(1b), Desmocollin type 4, Human BID coding sequence
Target Sequences: NM_001196 NP_001187.1 P55957

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (4)
Recombinant (12)
BID (16)
No (16)
6His, N-terminus (1)
GST (1)
His/GST,N-terminus (1)
His-SUMO (1)
His-T7 (3)
Myc-DDK (Flag) (5)
Human (10)
Mouse (3)
Rat (1)
293T Cells (2)
E. coli (10)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
BID Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.83 kDa
20 µg/$150
BID Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
11.1 kDa
20 µg/$150
BID Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
11.1 kDa
100 µg/$494
BID Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.83 kDa
100 µg/$494
BID Protein
Select
E. coli
His-SUMO
38 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
BID Protein - 12.5% SDS-PAGE of human BID stained with Coomassie Blue
Select
Wheat Germ Extract
GST
47.19 kDa
10 µg/$479; 25 µg/$670
BID Protein - Purified recombinant protein BID was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
21.8 kDa
20 µg/$1,107
Select
E. coli
None
22 kDa
100 µg/$721
Select
E. coli
His/GST,N-terminus
50 kDa
100 µg/$721
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
22.0 kDa
10 µg/$358; 50 µg/$479
BID Protein
Select
E. coli
None
100 µg/$511; 500 µg/$1,348; 20 µg/$311
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
21.99kD
10 µg/$269; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
BID Protein
Select
E. coli
6His, N-terminus
22 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949
Select
E. coli
His-T7
25.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
BID Protein - Recombinant BH3 Interacting Domain Death Agonist By SDS-PAGE
Select
E. coli
His-T7
25.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His-T7
26.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).