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BGN / Biglycan

biglycan

BGN / Biglycan is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Gene Name: biglycan
Synonyms: BGN, Bone/cartilage proteoglycan I, Biglycan, Biglycan proteoglycan, DSPG1, PG-S1, Small leucine-rich protein 1A, PGI, Bone/cartilage proteoglycan-I, SLRR1A
Target Sequences: NM_001711 NP_001702.1 P21810

Publications (2)

1
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H. Nature communications. 2016 7:12503. (IHC, WB, ELISA; Human) [Full Text Article] [PubMed:27527664] [PMC:PMC4990710]
2
Airn Regulates Igf2bp2 Translation in Cardiomyocytes. Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S. Circulation research. 2018 May;122:1347-1353. [Full Text Article] [PubMed:29483092] [PMC:PMC5948151]

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (13)
BGN / Biglycan (15)
No (15)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, C-terminus (2)
Fc (1)
GST (1)
His (7)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (9)
Mouse (3)
Rat (2)
293T Cells (1)
E. coli (9)
HEK 293 Cells (1)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (3)
BGN / Biglycan Protein
Select
E. coli
His, N-Terminal
39.4 kDa
50 µg/$419
BGN / Biglycan Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
BGN / Biglycan Protein - 12.5% SDS-PAGE of human BGN stained with Coomassie Blue
Select
Wheat Germ Extract
GST
66.22 kDa
10 µg/$479; 25 µg/$670
BGN / Biglycan Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.65 kDa
20 µg/$150
BGN / Biglycan Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
66.5 kDa
100 µg/$721
BGN / Biglycan Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.65 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.5 kDa
10 µg/$288; 50 µg/$436
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.47kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
BGN / Biglycan Protein - Recombinant Biglycan By SDS-PAGE
Select
E. coli
His
16.6 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
BGN / Biglycan Protein - Recombinant Biglycan By SDS-PAGE
Select
E. coli
His
14.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
BGN / Biglycan Protein - Recombinant Biglycan By SDS-PAGE
Select
E. coli
His
17.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His
14.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
BGN / Biglycan Protein - Recombinant Biglycan By SDS-PAGE
Select
E. coli
His
16.2 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
BGN / Biglycan Protein - Recombinant Biglycan By SDS-PAGE
Select
E. coli
His
16.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).