BCL2A1

BCL2-related protein A1

BCL2A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (9)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (4)

Recombinant (4)

Target

BCL2A1 (9)

Publications

No (9)

Tag

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (4)

Species

Human (7)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human BCL2A1 Protein (Recombinant His) - LS-G1760

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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BCL2A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124379

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.6 kDa

Price:

100 µg/$494

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BCL2A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116910

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20 kDa

Price:

100 µg/$494

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Human BCL2A1 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Thr2-Cys175) - LS-G26836

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

20.1 kDa

Price:

200 µl/$283

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Human BCL2A1 Protein (Recombinant GST) (Full Length) - LS-G27610

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

46.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BCL2A1 Protein (Recombinant GST) (Full Length) - LS-G27612

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

44.99 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BCL2A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74725

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20 kDa

Price:

20 µg/$150

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Human BCL2A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74722

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.6 kDa

Price:

20 µg/$150

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Human BCL2A1 Protein (Recombinant GST, N-terminus) (aa31-130) - LS-G57882

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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