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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BAX

BCL2-associated X protein

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.

Gene Name: BCL2-associated X protein
Family/Subfamily: Apoptosis , Not assigned-Other
Synonyms: BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
Target Sequences: NM_004324 NP_004315.1 Q07812

Publications (1)

1
Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions. Arduini A, Serviddio G, Escobar J, Tormos AM, Bellanti F, Via J, Monsalve M, Sastre J. American journal of physiology. Gastrointestinal and liver physiology. 2011 301:G119-27. [PubMed:21415417] Related Antibodies: LS-B1949.

Filtered By: None
Type
Cell-Based (1)
Competitive EIA (2)
Custom (5)
Sandwich (19)
Sandwich CLIA (3)
Target
BAX (30)
Reactivity
Human (8)
Mouse (9)
Rat (7)
Bovine (2)
Chicken (1)
Guinea pig (2)
Monkey (1)
Pig (1)
Rabbit (1)
Sample Type
Adherent Cell Cultures (1)
Cell Lysates (4)
Plasma (23)
Serum (23)
Tissue Homogenates (11)
Showing 1-25 of 30 results

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F10915
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Sandwich ELISA) - LS-F35416
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Sandwich ELISA) - LS-F35418
Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F35417
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $870.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Sandwich ELISA) - LS-F4142
Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $630.00
LSBio image for ELISA Kit

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F5064
Sandwich
96-Well Strip Plate
Rat
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $690.00
LSBio image for ELISA Kit

Bovine BAX ELISA Kit (Sandwich ELISA) - LS-F10916
Sandwich
96-Well Strip Plate
Bovine
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Monkey BAX ELISA Kit (Custom ELISA) - LS-F41619
Custom
96-Well Strip Plate
Monkey
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Guinea pig BAX ELISA Kit (Custom ELISA) - LS-F41618
Custom
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Chicken BAX ELISA Kit (Custom ELISA) - LS-F41615
Custom
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Sandwich ELISA) - LS-F52921
Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $975.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Sandwich ELISA) - LS-F51514
Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $740.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Custom ELISA) - LS-F16937
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1plate  $650.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Custom ELISA) - LS-F16938
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Sandwich ELISA) - LS-F21313
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F21494
Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Pig BAX ELISA Kit (Sandwich ELISA) - LS-F22660
Sandwich
96-Well Microplate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $660.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Sandwich ELISA) - LS-F22726
Sandwich
96-Well Microplate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Mouse/Human/Rat BAX ELISA Kit (Cell-Based ELISA) - LS-F1820
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $490.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Sandwich ELISA) - LS-F8604
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $650.00
LSBio image for ELISA Kit

Bovine BAX ELISA Kit (Sandwich ELISA) - LS-F8822
Sandwich
96-Well Strip Plate
Bovine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1plate  $740.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (CLIA) - LS-F29465
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (CLIA) - LS-F30524
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human BAX ELISA Kit (Sandwich ELISA) - LS-F26697
Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Mouse BAX ELISA Kit (Competitive EIA) - LS-F28212
Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit
Showing 1-25 of 30 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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