Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
BAMBI is a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
Gene Name: | BMP and activin membrane-bound inhibitor |
Synonyms: | BAMBI, NMA, Non-metastatic gene A protein |
Target Sequences: | NM_012342 NP_036474.1 Q13145 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.