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BAIAP2 / IRSP53

BAI1-associated protein 2

BAIAP2 / IRSP53 has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: BAI1-associated protein 2
Synonyms: BAIAP2, BAI-associated protein 2, BAI1-associated protein 2, BAP2, FLAF3, Fas ligand-associated factor 3, IRSP53, IRS-58, Protein BAP2, IRSp53/58
Target Sequences: NM_017450 NP_059344.1 Q9UQB8

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Products
Proteins (14)
Over-Expression Lysate (8)
Recombinant (6)
BAIAP2 / IRSP53 (14)
No (14)
DDK,C-terminus (1)
GST (1)
His (1)
Myc-DDK (Flag) (11)
Human (10)
293T Cells (4)
E. coli (1)
HEK 293 Cells (7)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purified (2)
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
60.7 kDa
100 µg/$494
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
57.2 kDa
20 µg/$150
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
57.3 kDa
20 µg/$150
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
60.7 kDa
20 µg/$215
Select
293T Cells
Myc-DDK (Flag)
60.7 kDa
20 µg/$150
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
60.7 kDa
100 µg/$710
BAIAP2 / IRSP53 Protein
Select
Sf9 Cells
DDK,C-terminus
57.2 kDa
20 µg/$677
BAIAP2 / IRSP53 Protein - 12.5% SDS-PAGE of human BAIAP2 stained with Coomassie Blue
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Wheat Germ Extract
GST
82.06 kDa
2 µg/$439
BAIAP2 / IRSP53 Protein - Purified recombinant protein BAIAP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
57.2 kDa
20 µg/$1,107
BAIAP2 / IRSP53 Protein - Purified recombinant protein BAIAP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
60.7 kDa
20 µg/$1,107
BAIAP2 / IRSP53 Protein - Purified recombinant protein BAIAP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
57.3 kDa
20 µg/$1,107
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
57.3 kDa
100 µg/$494
BAIAP2 / IRSP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
57.2 kDa
100 µg/$494
BAIAP2 / IRSP53 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-14 of 14 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).