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BAG2

BCL2-associated athanogene 2

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene Name: BCL2-associated athanogene 2
Synonyms: BAG2, Bcl-2-associated athanogene 2, Bcl2 binding protein bag2, BCL2-associated athanogene 2, BAG-2, DJ417I1.2
Target Sequences: NM_004282 NP_004273.1 O95816

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
BAG2 (8)
No (8)
6His, N-terminus (2)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (2)
Human (7)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (2)
BAG2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
BAG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.6 kDa
100 µg/$494
BAG2 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
BAG2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.9kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
BAG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.6 kDa
20 µg/$150
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.9 kDa
10 µg/$317; 50 µg/$524
BAG2 Protein - 12.5% SDS-PAGE of human BAG2 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.2 kDa
10 µg/$479; 25 µg/$670
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).