BAFF / TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis.

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Products

Proteins (30)

Type

Over-Expression Lysate (2)

Recombinant (28)

Target

BAFF / TNFSF13B (30)

Format

Animal-free (1)

Publications

No (30)

Tag

6His, N-terminus (1)

DDK (Flag) (2)

Fc (2)

Fc, N-terminus (2)

GST (1)

GST, N-terminus (1)

His (4)

His, N-Terminal (1)

His-DDK (Flag), N-terminus (1)

His-SUMO (1)

Human IgG1 Fc (1)

Mouse IgG1 Fc, N-terminus (1)

Myc-DDK (Flag) (3)

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Species

Human (25)

Mouse (4)

Source

293T Cells (1)

CHO Cells (4)

E. coli (12)

HEK 293 Cells (5)

Human (2)

Human Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (18)

Biologically Active

Biologically active (7)

Animal-free

Animal-free (1)

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Human BAFF / TNFSF13B Protein (Recombinant Fc, N-terminus) - LS-G137855

Source:

Mammalian Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human BAFF / TNFSF13B Protein (Recombinant GST) (Full Length) - LS-G32297

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.09 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BAFF / TNFSF13B Protein (Recombinant GST, N-terminus) (aa118-222) - LS-G61603

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse BAFF / TNFSF13B Protein (Recombinant Mouse IgG1 Fc, N-terminus) - LS-G146275

Source:

Human

Tag:

Mouse IgG1 Fc, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.9 kDa

Price:

10 µg/$290; 50 µg/$446

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Human BAFF / TNFSF13B Protein (Recombinant His, N-Terminal) - LS-G143829

Source:

E. coli

Tag:

His, N-Terminal

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

19.2 kDa

Price:

100 µg/$677

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Human BAFF / TNFSF13B Protein (Recombinant His-DDK (Flag), N-terminus) - LS-G142158

Source:

HEK 293 Cells

Tag:

His-DDK (Flag), N-terminus

Molecular Weight:

19 kDa

Price:

20 µg/$1,107

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Human BAFF / TNFSF13B Protein (Recombinant 6His, N-terminus) - LS-G146482

Source:

Human

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.3 kDa

Price:

10 µg/$331; 50 µg/$593

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Human BAFF / TNFSF13B Protein (Recombinant Fc) - LS-G24424

Source:

HEK 293 Cells

Tag:

Fc

Molecular Weight:

43.9 kDa

Price:

10 µg/$377; 50 µg/$752; 100 µg/$1,099

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Human BAFF / TNFSF13B Protein (Recombinant His-SUMO) (aa68-285) - LS-G22037

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

39.7 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human BAFF / TNFSF13B Protein (Recombinant) - LS-G27062

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

17 kDa (SDS-PAGE)

Price:

50 µg/$402; 10 µg/$262; 1 mg/$2,171

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Human BAFF / TNFSF13B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69143

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31 kDa

Price:

20 µg/$1,107

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Human BAFF / TNFSF13B Protein (Recombinant) (Ala134-Leu285) - LS-G97173

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17 kDa

Price:

100 µg/$1,159; 1 mg/$5,413

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Human BAFF / TNFSF13B Protein (Recombinant) (Ala134-Leu285) - LS-G97174

Source:

E. coli

Tag:

None

Molecular Weight:

17.2 kDa

Price:

20 µg/$360; 100 µg/$728

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Human BAFF / TNFSF13B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83927

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31 kDa

Price:

20 µg/$150

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BAFF / TNFSF13B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100850

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31 kDa

Price:

100 µg/$494

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Human BAFF / TNFSF13B Protein (Recombinant) (aa234-285) - LS-G5762

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

17.2 kDa

Price:

5 µg/$282; 100 µg/$1,466; 500 µg/$3,025

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Human BAFF / TNFSF13B Protein (Recombinant) - LS-G344

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

17.0 kDa

Price:

5 µg/$268; 20 µg/$349

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Human BAFF / TNFSF13B Protein (Recombinant) - LS-G3615

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

5 µg/$282; 20 µg/$370

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Human BAFF / TNFSF13B Protein (Recombinant) - LS-G137698

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

The 173 amino acid recombinant protein has a predicted molecular mass of approximately 19.2 kD. The protein migrates at approximately 20 kD in DTT-reducing and non-reducing conditions by SDS-PAGE. The predicted N-terminal amino acid is His.

Price:

10 µg/$306; 25 µg/$383; 100 µg/$869

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Mouse BAFF / TNFSF13B Protein (Recombinant) - LS-G137718

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

The 204 amino acid recombinant protein has a predicted molecular mass of approximately 22.8 kD. The DTT-reduced and non-reduced protein migrate at approximately 20-25 and 50-55 kD by SDS-PAGE respectively. The N-terminal contains a 9His-2(SGGG)-IEGR-tag.

Price:

10 µg/$355

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Human BAFF / TNFSF13B Protein (Recombinant Fc, N-terminus) (Ala134-Leu285) - LS-G139778

Source:

Mammalian Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.3 kDa

Price:

10 µg/$288; 50 µg/$436

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Human BAFF / TNFSF13B Protein (Recombinant His) (aa113-283) - LS-G14148

Source:

E. coli

Tag:

His

Molecular Weight:

20.6 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Mouse BAFF / TNFSF13B Protein (Recombinant His) (aa68-302) - LS-G14149

Source:

E. coli

Tag:

His

Molecular Weight:

27.7 kDa

Price:

10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Human BAFF / TNFSF13B Protein (Recombinant His) - LS-G3355

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human BAFF / TNFSF13B Protein (Recombinant DDK (Flag)) (aa134-285) - LS-G3878

Source:

E. coli

Tag:

DDK (Flag)

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~23kDa (SDS-PAGE)

Price:

10 µg/$365

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