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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BAF53B / ACTL6B

actin-like 6B

Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth.

Gene Name: actin-like 6B
Synonyms: ACTL6B, Actin-related protein Baf53b, ACTL6, Actin-like 6B, Actin-like 6, ArpNalpha, BAF53B, BRG1-associated factor 53B, Actin-like protein 6B, HArpN alpha
Target Sequences: NM_016188 NP_057272.1 O94805

Filtered By: None
Target
BAF53B / ACTL6B (17)
Reactivity
Human (17)
Mouse (6)
Rat (6)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Pig (4)
Rabbit (4)
Application
IHC (12)
IHC-P (3)
WB (16)
Flo (8)
ELISA (10)
IF (2)
Host
rabbit (17)
Isotype
IgG (14)
Clonality
polyclonal pc (17)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (8)
Epitope
aa42-70 (8)
aa323-372 (4)
aa1-280 (2)
Publications
No (17)
Showing 1-17 of 17 results

BAF53B / ACTL6B Antibody (aa42-70) IHC-plus™ LS-B12788
Rabbit Polyclonal to Human BAF53B / ACTL6B
Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTL6B Antibody western blot of NCI-H460,HepG2 cell line lysates (35 ug/lane). The ACTL6B antibody detected the ACTL6B protein (arrow).
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTL6B Antibody western blot of NCI-H460,HepG2 cell line lysates (35 ug/lane). The ACTL6B antibody detected the ACTL6B protein (arrow).

BAF53B / ACTL6B Antibody (aa42-70) LS-C319306
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

BAF53B / ACTL6B Antibody (aa42-70, Biotin) LS-C207986
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $635.00

BAF53B / ACTL6B Antibody (aa42-70, FITC) LS-C207987
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

BAF53B / ACTL6B Antibody (aa42-70, AP) LS-C207982
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

BAF53B / ACTL6B Antibody (aa42-70, APC) LS-C207983
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

BAF53B / ACTL6B Antibody (aa42-70, PE) LS-C207989
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
PE Conjugated
200µl  $680.00

BAF53B / ACTL6B Antibody (aa42-70, Azide-free, HRP) LS-C207988
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

BAF53B / ACTL6B Antibody LS-C346230
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human kidney tissue.
Immunohistochemistry of paraffin-embedded human kidney cancer tissue.
Immunohistochemistry of paraffin-embedded human kidney tissue.
Immunohistochemistry of paraffin-embedded human kidney cancer tissue.

BAF53B / ACTL6B Antibody (aa1-280) LS-C375133
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human brain using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human brain using antibody at 1:100 dilution.

BAF53B / ACTL6B Antibody LS-C412733
Rabbit Polyclonal to Human BAF53B / ACTL6B
Mouse, Rat, Human
IF IHC WB
Unconjugated
100µl  $385.00

BAF53B / ACTL6B Antibody (aa1-280) LS-C375127
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human brain using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human brain using antibody at 1:100 dilution.

BAF53B / ACTL6B Antibody LS-C137311
Rabbit Polyclonal to Human BAF53B / ACTL6B
Human
ELISA WB
Unconjugated
100µl  $255.00

BAF53B / ACTL6B Antibody (aa323-372) LS-C107817
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BAF53B / ACTL6B Antibody (aa323-372, HRP) LS-C462525
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BAF53B / ACTL6B Antibody (aa323-372, Biotin) LS-C462523
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BAF53B / ACTL6B Antibody (aa323-372, FITC) LS-C462524
Rabbit Polyclonal (IgG) to Human BAF53B / ACTL6B
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACTL6B / BAF53B antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-17 of 17 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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