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B4GALT3

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

B4GALT3 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
Synonyms: B4GALT3, B4Gal-T3, Beta-1,4-GalTase 3, Beta4Gal-T3
Target Sequences: NM_003779 NP_003770.1 O60512

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
B4GALT3 (6)
No (6)
6His, C-terminus (2)
GST (2)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
41.5 kDa
10 µg/$344; 50 µg/$584
B4GALT3 Protein - 12.5% SDS-PAGE of human B4GALT3 stained with Coomassie Blue
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Wheat Germ Extract
GST
70.3 kDa
2 µg/$439
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E. coli
GST
67.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
B4GALT3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43.7 kDa
20 µg/$150
B4GALT3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43.7 kDa
100 µg/$494
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
41.5kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).