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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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B3GNT3 / TMEM3
Udp-glcnac:betagal Beta-1,3-n-acetylglucosaminyltransferase 3
B3GNT3 / TMEM3 is a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
| Gene Name: | Udp-glcnac:betagal Beta-1,3-n-acetylglucosaminyltransferase 3 |
| Synonyms: | B3GNT3, B3GALT8, B3GNT-3, Beta-3-Gx-T8, Beta3Gn-T3, BGnT-3, B3GAL-T8, Beta3Gal-T8, Beta3GalT8, B3GN-T3, Beta-1,3-GalTase 8, Beta-1,3-Gn-T3, Core1-beta3GlcNAcT, HP10328, Transmembrane protein 3, TMEM3 |
| Target Sequences: | NM_014256 NP_055071.2 Q9Y2A9 |
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