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B3GAT3

beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)

Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.

Gene Name: beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Synonyms: B3GAT3, GLCATI, Glucuronosyltransferase I, GlcAT-I, Sqv-8-like protein, GlcUAT-I
Target Sequences: NM_012200 NP_036332.2 O94766

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
B3GAT3 (8)
No (8)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
B3GAT3 Protein - 12.5% SDS-PAGE of human B3GAT3 stained with Coomassie Blue
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Wheat Germ Extract
GST
63.5 kDa
10 µg/$479; 25 µg/$670
B3GAT3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.9 kDa
20 µg/$150
B3GAT3 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
B3GAT3 Protein - Purified recombinant protein B3GAT3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
36.9 kDa
20 µg/$1,107
B3GAT3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
B3GAT3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.9 kDa
100 µg/$494
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.4 kDa
10 µg/$376; 50 µg/$526
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.4kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).