ATXN3 / JOS

ataxin 3

Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.

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Products

Proteins (15)

Type

Over-Expression Lysate (10)

Recombinant (5)

Target

ATXN3 / JOS (15)

Publications

No (15)

Tag

DDK,C-terminus (1)

GST (2)

Myc-DDK (Flag) (11)

Species

Human (10)

Source

293T Cells (5)

E. coli (1)

HEK 293 Cells (6)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

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ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124704

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.5 kDa

Price:

100 µg/$494

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ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128013

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

100 µg/$494

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ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128916

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

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ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116270

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.1 kDa

Price:

100 µg/$494

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ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109446

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

100 µg/$494

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Human ATXN3 / JOS Protein (Recombinant DDK,C-terminus) - LS-G142484

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

41.1 kDa

Price:

20 µg/$677

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Human ATXN3 / JOS Protein (Recombinant GST) (Full Length) - LS-G29338

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

35.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ATXN3 / JOS Protein (Recombinant GST) (Full Length) - LS-G29339

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ATXN3 / JOS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66214

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.1 kDa

Price:

20 µg/$1,107

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Human ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77183

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.5 kDa

Price:

20 µg/$150

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Human ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77184

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

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Human ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77185

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

20 µg/$150

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Human ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77186

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

20 µg/$150

Select

Human ATXN3 / JOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77187

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.1 kDa

Price:

20 µg/$150

Select

Human ATXN3 / JOS Protein (Recombinant) - LS-G564

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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