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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATRIP

ATR interacting protein

ATRIP is an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATR interacting protein
Synonyms: ATRIP, AGS1, ATR-interacting protein, ATR interacting protein
Target Sequences: NM_130384 NP_569055.1 Q8WXE1

Publications (1)

1
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Choi JH, Lindsey-Boltz LA, Sancar A. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:13301-6. [PubMed:17686975] [PMC:PMC1941640]

Filtered by: None
Target
ATRIP (54)
Reactivity
Human (54)
Mouse (18)
Rat (14)
Bovine (1)
Dog (2)
Monkey (2)
Non-Human Primate (1)
Sheep (1)
Application
IHC (20)
IHC-P (7)
WB (44)
Flo (5)
DB (8)
ELISA (19)
ICC (2)
IF (15)
IP (13)
Peptide-ELISA (4)
Host
rabbit (44)
mouse (10)
Isotype
IgG (28)
IgG1 (2)
IgG2a (4)
IgG2b (4)
Clonality
monoclonal mc (10)
polyclonal pc (44)
Clone
OTI1F10 (2)
OTI1G6 (2)
OTI4A8 (2)
OTI5E7 (2)
OTI9A4 (2)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (5)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (44)
Epitope
pSer239 (9)
aa42-309 (7)
aa500-550 (6)
pSer224 (3)
pSer68 (3)
10-90 aa (2)
160-240 aa (2)
aa1-182 (2)
aa1-260 (2)
aa100-150 (2)
Asp64 (1)
N-Terminus (1)
aa190-239 (1)
aa34-83 (1)
Publications
No (54)
Showing 1-25 of 54 results

IHC-plus™ ATRIP Antibody (aa190-239) LS-B13319
Rabbit Polyclonal (IgG) to Human ATRIP
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl 1mg/ml  $505.00
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

ATRIP Antibody (clone OTI5E7) LS-C173897
Mouse Monoclonal [clone OTI5E7] (IgG2a) to Human ATRIP
Dog, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl 1.13mg/ml  $345.00
IHC of paraffin-embedded Human breast tissue using anti-ATRIP mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-ATRIP mouse monoclonal antibody.

ATRIP Antibody (aa42-309, clone OTI5E7, Carrier-free) LS-C799763
Mouse Monoclonal [clone OTI5E7] (IgG2a) to Human ATRIP
Dog, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

ATRIP Antibody (N-Terminus) LS-C354219
Rabbit Polyclonal to Human ATRIP
Mouse, Rat, Human
Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of ATRIP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of ATRIP staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

ATRIP Antibody (aa34-83) LS-C117796
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ATRIP Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of HeLa cells, using ATRIP Antibody. The picture on the right is blocked with the synthesized peptide.

ATRIP Antibody (phospho-Ser224) LS-C198656
Rabbit Polyclonal (IgG) to Human ATRIP
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using ATRIP (Phospho-Ser224) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from 293 cells treated with UV 15', using ATRIP (Phospho-Ser224) Antibody. The lane on the right is blocked with the phospho peptide.

ATRIP Antibody LS-C417660
Rabbit Polyclonal to Human ATRIP
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg  $305.00
Western blot of ATRIP expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

ATRIP Antibody (phospho-Ser239) LS-C158595
Rabbit Polyclonal to Human ATRIP
Human
DB
Unconjugated
400µl  $325.00
Dot blot of Phospho-ATRIP-S239 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

ATRIP Antibody LS-C346249
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Human
IF, IHC, IP, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of A549 cells.
Western blot analysis of extracts of various cell lines.

ATRIP Antibody (aa1-260) LS-C378840
Rabbit Polyclonal (IgG) to Human ATRIP
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human ovary using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human ovarian cancer using ATRIP Antibody at dilution of 1:100

ATRIP Antibody (10-90 aa) LS-C382215
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of ATRIP antibody
Western blot of ATRIP antibody

ATRIP Antibody (Asp64) LS-C176386
Rabbit Polyclonal to Human ATRIP
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of ATRIP (D64) pAb in paraffin-embedded human lung colon carcinoma tissue.
Western blot of ATRIP (D64) pAb in extracts from NIH/3T3 cells treated with PMA 125ng/ml 30'.

ATRIP Antibody (aa42-309, clone OTI9A4) LS-C337714
Mouse Monoclonal [clone OTI9A4] (IgG2a) to Human ATRIP
Human, Monkey
Flo, IF, WB
Unconjugated
100µl 1.05mg/ml  $345.00
Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
Western blot of extracts (35ug) from 9 different cell lines by using anti-ATRIP monoclonal antibody.

ATRIP Antibody (aa42-309, clone OTI9A4, Carrier-free) LS-C797576
Mouse Monoclonal [clone OTI9A4] (IgG2a) to Human ATRIP
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100µg  $395.00

ATRIP Antibody (aa1-182) LS-C12046
Rabbit Polyclonal to Human ATRIP
Human
ELISA, IHC, IP, WB
Unconjugated
50µg  $445.00

ATRIP Antibody (aa1-182) LS-C355588
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Human
IF, IP, WB
Unconjugated
100µg  $425.00
IF using ATRIP Antibody
IF using ATRIP Antibody

ATRIP Antibody LS-C412754
Rabbit Polyclonal to Human ATRIP
Mouse, Human
IF, IHC, WB
Unconjugated
100µl  $385.00

ATRIP Antibody (phospho-Ser68) LS-C801217
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

ATRIP Antibody LS-C801491
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

ATRIP Antibody (phospho-Ser224) LS-C801508
Rabbit Polyclonal (IgG) to Human ATRIP
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

ATRIP Antibody (160-240 aa) LS-C381407
Rabbit Polyclonal (IgG) to Human ATRIP
Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

ATRIP Antibody (aa42-309, clone OTI4A8) LS-C337713
Mouse Monoclonal [clone OTI4A8] (IgG2b) to Human ATRIP
Human
IF, WB
Unconjugated
100µl 1mg/ml  $345.00
Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATRIP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATRIP.

ATRIP Antibody (aa42-309, clone OTI4A8, Carrier-free) LS-C799423
Mouse Monoclonal [clone OTI4A8] (IgG2b) to Human ATRIP
Human
IF, WB
Unconjugated, Carrier-free
100µg  $395.00

ATRIP Antibody (aa100-150) LS-C287538
Rabbit Polyclonal (IgG) to Human ATRIP
Human
IHC, IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human ATRIP by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-ATRIP used at a dilution of 1:1000 (1 ug/ml).

ATRIP Antibody LS-C417235
Rabbit Polyclonal to Human ATRIP
Mouse, Rat, Human
IHC, WB
Unconjugated
100µg  $305.00
Showing 1-25 of 54 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).