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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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ATP8B1 / BRIC

ATPase, aminophospholipid transporter, class I, type 8B, member 1

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. May have a role in transport of bile acids into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Together with TMEM30A is involved in uptake of the synthetic drug alkylphospholipid perifosine. Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. May act as cardiolipin transporter during inflammatory injury.

Gene Name: ATPase, aminophospholipid transporter, class I, type 8B, member 1
Family/Subfamily: Transporter , ATPase - P type, type IV
Synonyms: ATP8B1, ATPIC, BRIC, FIC1, E1-E2 ATPase, ICP1, PFIC1, PFIC
Target Sequences: NM_005603 NP_005594.1 O43520

☰ Filters
3F10 (1)
No (6)
Viewing 1-6 of 6 items
ATP8B1 / BRIC Antibody - Detection limit for recombinant GST tagged ATP8B1 is 1 ng/ml as a capture antibody.
Select
Mouse Monoclonal [clone 3F10] (IgG1,k) to Human ATP8B1 / BRIC
Human
ELISA
Unconjugated
100µg   $365.00
ATP8B1 / BRIC Antibody - IHC on paraffin sections of human bowel tissue using Rabbit antibody to ATP8B1. HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through 0.2 µm. Detection was done using Novolink HRP polymer. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.
Select
Rabbit-New Zealand White Polyclonal to Human ATP8B1 / BRIC
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $325.00
ATP8B1 / BRIC Antibody - Immunofluorescent analysis of HepG2 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
Rabbit Polyclonal (IgG) to Human ATP8B1 / BRIC
Human
ELISA, IF
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ATP8B1 / BRIC
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ATP8B1 / BRIC
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ATP8B1 / BRIC
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00

Viewing 1-6 of 6 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).