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ATP8A1

Atpase, Aminophospholipid Transporter (Aplt), Class I, Type 8a, Member 1

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Gene Name: Atpase, Aminophospholipid Transporter (Aplt), Class I, Type 8a, Member 1
Family/Subfamily: Transporter , ATPase - P type, type IV
Synonyms: ATP8A1, ATPASEII, ATPIA, ATPase II, Chromaffin granule ATPase II, Aminophospholipid translocase, ATPP2
Target Sequences: NM_006095 NP_006086.1 Q9Y2Q0

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Products
Antibodies (9)
Primary (9)
ATP8A1 (9)
Human (9)
Mouse (4)
Rat (2)
IHC (4)
IHC-P (1)
WB (5)
ELISA (5)
IF (1)
Peptide-ELISA (1)
rabbit (7)
rabbit-new zealand white (2)
IgG (7)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
aa2-50 (1)
aa550-600 (1)
No (9)
ATP8A1 Antibody - Immunohistochemistry of paraffin-embedded human appendix tissue at dilution of 1:100
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ATP8A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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ATP8A1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ATP8A1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ATP8A1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ATP8A1 Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ATP8A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ATP8A1 Rabbit-New Zealand White anti-Human Polyclonal (aa550-600) Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$393
Select
ATP8A1 Rabbit-New Zealand White anti-Human Polyclonal (aa2-50) Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$393
Select
ATP8A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
ATP8A1 Antibody - Western blot analysis of extracts of various cells.
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ATP8A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).