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ATP6V1G1 / ATP6J

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1

ATP6V1G1 / ATP6J is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized.

Gene Name: ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
Family/Subfamily: Transporter , ATPase - V type
Synonyms: ATP6V1G1, ATP6GL, ATP6J, Atp1v1g1, ATP6G, ATP6G1, V-ATPase 13 kDa subunit 1, V-ATPase G subunit 1, Vma10, V-ATPase subunit G 1
Target Sequences: NM_004888 NP_004879.1 O75348

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).